Because I took a while to write it up elsewhere, I figured I'm archive a copy here as well.
Wow this list got long... sorry
Beau of the Fifth Column has a pretty interesting take on events, a strong interest in community networks, and deep insight into what holds society together - https://www.youtube.com/c/BeauoftheFifthColumn
Breaking Points - Krystal Ball is a liberal, Saagar Enjeti is a conservative, and together they seek to cover the important stories that would otherwise go unnoticed -
https://www.youtube.com/c/breakingpoints
Knowing Better is an ex soldier who offers long insightful views on a variety of topics - https://www.youtube.com/c/KnowingBetter
Lex Fridman was born in the Soviet Union, worked at MIT in AI, and does interesting interviews with a wide variety of people - https://www.youtube.com/c/lexfridman
MKBHD reviews technology in a fairly credible way - https://www.youtube.com/c/mkbhd
MrPete222 is the shop teacher you never had - fascinating lessons and stories about machining - https://www.youtube.com/c/mrpete222
Phil DeDranco does a daily rundown of the stories that you might get in the media, with a fairly balanced view - https://www.youtube.com/c/PhilipDeFranco
Practical Engineering is an explainer channel about most things infrastructure - https://www.youtube.com/c/PracticalEngineeringChannel
Rebecca Watson provides a welcome skeptical view and calls out quite a lot of BS related to science - https://www.youtube.com/skepchicks
Rebel Wisdom is a project that is actively trying to figure out collective sense making in the modern era - https://www.youtube.com/c/RebelWisdom
Sabine Hossenfelder is a commenter on all things physics - https://www.youtube.com/c/SabineHossenfelder
Scott Manley provides commentary on all things space and rocket related - https://www.youtube.com/c/szyzyg
Smarter Every Day is an engineer who provides interesting explainers about various subjects. He got permission to film and interview inside an active US nuclear attack sub... pretty cool - https://www.youtube.com/c/smartereveryday
Technology connections does in depth explainers of everyday stuff you didn't realize you wanted to know more about, like how heat pumps or lanterns work. - https://www.youtube.com/c/TechnologyConnections
Veritasium was founded by Derek Muller, who was looking for more effective ways of teaching, when he found that traditional education has almost zero effect at removing misconceptions - https://www.youtube.com/c/veritasium
ZDogg is an MD who gives strong personal opinions on all things medical - https://www.youtube.com/c/ZDoggMD